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Gabriel García Márquez, Nobel Prize-winning explorer of myth and reality, dies at 87
Gabriel García Márquez, the Nobel Prize-winning Colombian writer who immersed the world in the powerful currents of magic realism, creating a literary style that blended reality, myth, love and loss in a series of emotionally rich novels that made him one of the most revered and influential writers of the 20th century, died April 17 at his home in Mexico City. He was 87.

The Associated Press reported his death. In July 2012, his brother Jaime García Márquez announced that the author had dementia.
Mr. García Márquez, who was affectionately known throughout Latin America as “Gabo,” was a journalist, novelist, screenwriter, playwright, memoirist and student of political history and modernist literature. Through the strength of his writing, he became a cultural icon who commanded a vast public following and who sometimes drew fire for his unwavering support of Cuban leader Fidel Castro.

In his novels, novellas and short stories, Mr. García Márquez addressed the themes of love, loneliness, death and power. Critics generally rank “One Hundred Years of Solitude” (1967), “The Autumn of the Patriarch” (1975) and “Love in the Time of Cholera” (1985) as his masterpieces.
“The world has lost one of its greatest visionary writers — and one of my favorites from the time I was young,” President Obama said in a statement, calling the author “a representative and voice for the people of the Americas.”
Mr. García Márquez established his reputation with “One Hundred Years of Solitude,” an epic novel about multiple generations of the Buendía family in the fantastical town of Macondo, a lush settlement based on the author’s birthplace on the Caribbean coast of Colombia. The novel explored social, economic and political ideas in a way that captured the experience of an entire continent, but it also included supernatural elements, such as a scene in which a young woman ascends to heaven while folding the family sheets.

Gabriel García Márquez, Nobel Prize-winning explorer of myth and reality, dies at 87

Gabriel García Márquez, the Nobel Prize-winning Colombian writer who immersed the world in the powerful currents of magic realism, creating a literary style that blended reality, myth, love and loss in a series of emotionally rich novels that made him one of the most revered and influential writers of the 20th century, died April 17 at his home in Mexico City. He was 87.

The Associated Press reported his death. In July 2012, his brother Jaime García Márquez announced that the author had dementia.

Mr. García Márquez, who was affectionately known throughout Latin America as “Gabo,” was a journalist, novelist, screenwriter, playwright, memoirist and student of political history and modernist literature. Through the strength of his writing, he became a cultural icon who commanded a vast public following and who sometimes drew fire for his unwavering support of Cuban leader Fidel Castro.

In his novels, novellas and short stories, Mr. García Márquez addressed the themes of love, loneliness, death and power. Critics generally rank “One Hundred Years of Solitude” (1967), “The Autumn of the Patriarch” (1975) and “Love in the Time of Cholera” (1985) as his masterpieces.

“The world has lost one of its greatest visionary writers — and one of my favorites from the time I was young,” President Obama said in a statement, calling the author “a representative and voice for the people of the Americas.”

Mr. García Márquez established his reputation with “One Hundred Years of Solitude,” an epic novel about multiple generations of the Buendía family in the fantastical town of Macondo, a lush settlement based on the author’s birthplace on the Caribbean coast of Colombia. The novel explored social, economic and political ideas in a way that captured the experience of an entire continent, but it also included supernatural elements, such as a scene in which a young woman ascends to heaven while folding the family sheets.

(出典: Washington Post)

Heartbleed bug fixes threaten to cause major Internet disruptions in coming weeks

Efforts to fix the notorious Heartbleed bug threaten to cause major disruptions to the Internet over the next several weeks as companies scramble to repair encryption systems on hundreds of thousands of Web sites at the same time, security experts say.

Estimates of the severity of the bug’s damage have mounted almost daily since researchers announced the discovery of Heartbleed last week. What initially seemed like an inconvenient matter of changing passwords for protection now appears much more serious. New revelations suggest that skilled hackers can use the bug to create fake Web sites that mimic legitimate ones to trick consumers into handing over valuable personal information.

The sheer scale of the work required to fix this aspect of the bug — which makes it possible to steal the “security certificates” that verify that a Web site is authentic — could overwhelm the systems designed to keep the Internet trustworthy.

“Imagine if we found out all at once that all the doors everybody uses are all vulnerable — they can all get broken into,” said Jason Healey, a cybersecurity scholar at the Washington-based Atlantic Council. “The kinds of bad things it enables is largely limited only by the imagination of the bad guys.”

The Heartbleed bug put many consumers’ user names and passwords at risk. Undetected for two years, the bug quietly undermined the basic security of the Internet by leaving a gap in OpenSSL, an encryption technology used widely by businesses to protect sensitive data. By some estimates, the bug affected as much as two-thirds of the Internet; the flaw prompted thousands of Web users to change their passwords on Google, Yahoo, Facebook and other major services.


Deadly Chile blaze destroys 500 homes
Seven confirmed dead in port of Valparaíso as thousands evacuated and city declared catastrophe zone



A fire raging in the Chilean port city of Valparaíso has killed at least seven people and destroyed 500 homes, according to officials. Thousands of residents have been evacuated, including more than 200 inmates at a women’s prison.
Firefighters struggled as high winds rained hot ash over the wooden houses and narrow streets of the city of 250,000, where people use staircases to reach neighbourhoods that hug steep hills between the forest and the sea.
"This is the worst disaster I have seen," said the regional governor, Ricardo Bravo. "Now we fear that the fire will spread to the centre of the city, which would increase the severity of the emergency."
President Michelle Bachelet arrived on Sunday to oversee emergency operations. She declared the city a catastrophe zone, putting Chile's military in charge of maintaining order as the homes of more than 5,000 people were evacuated amid the smoke and flames.
Seven people were confirmed dead, said police general Julio Pineda, and the toll was expected to rise.
It was the worst fire to hit the picturesque seaside city since 1953, when 50 people were killed and every structure was destroyed on several of the city’s hills.

Deadly Chile blaze destroys 500 homes

Seven confirmed dead in port of Valparaíso as thousands evacuated and city declared catastrophe zone

A fire raging in the Chilean port city of Valparaíso has killed at least seven people and destroyed 500 homes, according to officials. Thousands of residents have been evacuated, including more than 200 inmates at a women’s prison.

Firefighters struggled as high winds rained hot ash over the wooden houses and narrow streets of the city of 250,000, where people use staircases to reach neighbourhoods that hug steep hills between the forest and the sea.

"This is the worst disaster I have seen," said the regional governor, Ricardo Bravo. "Now we fear that the fire will spread to the centre of the city, which would increase the severity of the emergency."

President Michelle Bachelet arrived on Sunday to oversee emergency operations. She declared the city a catastrophe zone, putting Chile's military in charge of maintaining order as the homes of more than 5,000 people were evacuated amid the smoke and flames.

Seven people were confirmed dead, said police general Julio Pineda, and the toll was expected to rise.

It was the worst fire to hit the picturesque seaside city since 1953, when 50 people were killed and every structure was destroyed on several of the city’s hills.

'I am deeply sorry': Japanese scientist breaks down in tears as she apologises for 'falsifying' stem cell research paper

  • Haruko Obokata, 30, accused of falsifying data in stem cell report
  • Claimed ordinary cells could be turned into stem cells using acid
  • Using person’s own cells to grow organs reduces risk of rejection
  • However Obokata’s employer says she used wrong images in report
  • She is accused of altering one image and making mistakes in her data
  • Despite challenging claims, Obokata forced into humiliating apology
  • She choked back tears today as she bowed her head in shame

A Japanese scientist who published a paper claiming ordinary cells could be turned into stem cells by bathing them in acid has today been forced to apologise after she was accused of falsifying data.

Haruko Obokata, 30, choked back tears during a televised news conference packed with hundreds of reporters, but insisted she did not tamper with the data to fabricate results.

She said she did not agree with retracting the research, claiming that cell transformation had been ‘confirmed many times for a fact’ and vowed to prove it if she is allowed back into a lab.

She has contested allegations of research malpractice made by a panel of scientists at the government-funded Riken Center for Development Biology, where she is employed.

Obokata said the company had advised her not to speak publicly about the controversy and today’s press conference, which lasted for over two hours, marks her first public appearance in weeks.

The decision to appear was made despite doctors’ orders to stay at home after she went to hospital for treatment treatment Monday.

(出典: Daily Mail)

At least 4 killed in shooting at Fort Hood; gunman among dead
A soldier opened fire Wednesday at Fort Hood, killing three people and wounding several others before taking his own life, law enforcement sources told CBS News.The incident occurred Wednesday afternoon at Fort Hood, the site of a notorious 2009 mass shooting.Law enforcement sources said four people were killed, including the gunman, who died of a self-inflicted wound. Officials said several people were wounded, although the exact number was not immediately clear. At one point there were reports that as many as 14 people had been wounded.Sources told CBS News the shooter had been identified as 34-year-old soldier Ivan Lopez. A source said the violence apparently stemmed from some sort of soldier dispute. In Chicago, President Barack Obama said he was following the situation closely. Defense Secretary Chuck Hagel was also informed, Navy Rear Adm. John Kirby said."We’re heartbroken that something like this might have happened again," Obama said, referring to the 2009 massacre. "I want to just assure all of us we are going to get to the bottom of what happened."Warning sirens went off on Wednesday afternoon and all personnel were urged to shelter in place as the base went on lockdown.

 "There has been a shooting at Fort Hood and injuries are reported. Emergency crews are on the scene. No further details are known at this time," the post said in a brief statement.

At least 4 killed in shooting at Fort Hood; gunman among dead

A soldier opened fire Wednesday at Fort Hood, killing three people and wounding several others before taking his own life, law enforcement sources told CBS News.

The incident occurred Wednesday afternoon at Fort Hood, the site of a notorious 2009 mass shooting.

Law enforcement sources said four people were killed, including the gunman, who died of a self-inflicted wound. Officials said several people were wounded, although the exact number was not immediately clear. At one point there were reports that as many as 14 people had been wounded.

Sources told CBS News the shooter had been identified as 34-year-old soldier Ivan Lopez. A source said the violence apparently stemmed from some sort of soldier dispute.

In Chicago, President Barack Obama said he was following the situation closely. Defense Secretary Chuck Hagel was also informed, Navy Rear Adm. John Kirby said.

"We’re heartbroken that something like this might have happened again," Obama said, referring to the 2009 massacre. "I want to just assure all of us we are going to get to the bottom of what happened."

Warning sirens went off on Wednesday afternoon and all personnel were urged to shelter in place as the base went on lockdown.

"There has been a shooting at Fort Hood and injuries are reported. Emergency crews are on the scene. No further details are known at this time," the post said in a brief statement.

(出典: cbsnews.com)

Chile assesses damage after massive quake, tsunami

Chilean authorities on Wednesday were assessing the damage from a massive earthquake that struck off the northern coast, causing a small tsunami, but the impact was mostly limited, according to early indications.

Thousands of people who evacuated the country’s low-lying coastal areas returned home on Wednesday morning after authorities called off a tsunami alarm.

The 8.2 magnitude quake that shook northern Chile on Tuesday killed six people and triggered a tsunami that pounded the shore with 2-meter (7-foot) waves.

Authorities evaluated the damage on Wednesday as the ocean waves receded and daylight showed the full extent of the outcome.

Mines in Chile, the world’s No. 1 copper producer, mostly said they were functioning normally, and oil refineries reported normal operations.

The arid, mineral-rich north is sparsely populated, with most of the population concentrated in the port towns of Iquique and Arica, near the Peruvian border.

In Peru, the earthquake led to temporary power outages and evacuations in some southern towns, but did not cause serious damage or injuries.

Chilean President Michelle Bachelet visited the affected area on Wednesday. She declared a disaster zone, promising troops and police reinforcements to maintain order while damage was repaired after landslides blocked a number of roads.

Local television showed smaller fishing vessels badly damaged and overturned in Iquique. Although the tsunami alert was called off, the navy warned that high waves and strong currents could continue, and ports in the area remained closed.

Several smaller aftershocks, some as big as 5.2 magnitude, were registered over Tuesday night and Wednesday morning, according to Chile’s emergency office.

Over 900,000 people were evacuated from the coastline along Chile on Tuesday, according to the government’s emergency office, in a move that local media reported took place in a largely orderly fashion.

(出典: reuters.com)

Japanese Institute Said It Found Misconduct in Stem-Cell Studies
Riken Investigated Plagiarism Allegations in 2 Papers Published in Nature
Japan’s leading research institute on Tuesday said it found evidence of scientific misconduct in disputed studies on stem cells led by one of its scientists.
Riken, a prestigious, government-funded institute, has been investigating allegations of irregularities in images and plagiarism in two papers published in the journal Nature in late January.
In its final report on its probe, Riken said there was research misconduct on two points, saying Haruko Obokata, the lead author of the papers, “acted in a manner that can by no means be permitted” when she manipulated “the image data of two different gels and using data from two different experiments.”
"Given the poor quality of her laboratory notes it has become clearly evident that it will be extremely difficult for anyone else to accurately trace or understand her experiments," it said.
Riken’s president, Nobel laureate Ryoji Noyori, was scheduled to speak later Tuesday about the report, but Riken said Dr. Obokata wouldn’t speak to the media. Dr. Obokata has been out of the public eye since doubts began to be raised over her research soon after the publication of the papers.
Emails to Dr. Obokata were returned by a lawyer who said he was representing Dr. Obokata. He said before the results of the probe were released that Dr. Obokata wouldn’t express her opinions until the results were out.
On March 14, Riken released an interim report, saying the study contained “serious errors.” At the time, the institute said it was examining whether to retract the papers, which had appeared to offer a revolutionary new approach to creating stem cells.
The interim report concluded that there was “inappropriate handling” of data in two instances, but it said those instances didn’t amount to research misconduct. It said at the time that the investigation was continuing into the most serious allegations—in particular, the question of why three images in the papers were nearly identical to three images included in Dr. Obokata’s 2011 doctoral dissertation at Japan’s Waseda University.
The controversy has highlighted the race for improved methods of creating stem cells, long seen as a potential source of cures for heart disease, diabetes and other ailments. It has also pointed to apparent lax controls at one of Japan’s top scientific institutions.

Japanese Institute Said It Found Misconduct in Stem-Cell Studies

Riken Investigated Plagiarism Allegations in 2 Papers Published in Nature

Japan’s leading research institute on Tuesday said it found evidence of scientific misconduct in disputed studies on stem cells led by one of its scientists.

Riken, a prestigious, government-funded institute, has been investigating allegations of irregularities in images and plagiarism in two papers published in the journal Nature in late January.

In its final report on its probe, Riken said there was research misconduct on two points, saying Haruko Obokata, the lead author of the papers, “acted in a manner that can by no means be permitted” when she manipulated “the image data of two different gels and using data from two different experiments.”

"Given the poor quality of her laboratory notes it has become clearly evident that it will be extremely difficult for anyone else to accurately trace or understand her experiments," it said.

Riken’s president, Nobel laureate Ryoji Noyori, was scheduled to speak later Tuesday about the report, but Riken said Dr. Obokata wouldn’t speak to the media. Dr. Obokata has been out of the public eye since doubts began to be raised over her research soon after the publication of the papers.

Emails to Dr. Obokata were returned by a lawyer who said he was representing Dr. Obokata. He said before the results of the probe were released that Dr. Obokata wouldn’t express her opinions until the results were out.

On March 14, Riken released an interim report, saying the study contained “serious errors.” At the time, the institute said it was examining whether to retract the papers, which had appeared to offer a revolutionary new approach to creating stem cells.

The interim report concluded that there was “inappropriate handling” of data in two instances, but it said those instances didn’t amount to research misconduct. It said at the time that the investigation was continuing into the most serious allegations—in particular, the question of why three images in the papers were nearly identical to three images included in Dr. Obokata’s 2011 doctoral dissertation at Japan’s Waseda University.

The controversy has highlighted the race for improved methods of creating stem cells, long seen as a potential source of cures for heart disease, diabetes and other ailments. It has also pointed to apparent lax controls at one of Japan’s top scientific institutions.

(出典: The Wall Street Journal)

Crimean chief prosecutor Natalia Poklonskaya ‘wanted’ by Ukraine’s security service


Ukrainian national security service has put Crimea’s chief prosecutor Natalia Poklonskaya on its wanted list. She is charged of taking actions aimed at the violent overthrow of constitutional order and takeover of government power.

Poklonskaya took the office as Crimea defied the coup-imposed government in Kiev and sought independence from Ukraine. After the peninsula joined the Russian Federation, she was appointed as Crimea’s acting chief prosecutor by Russia’s General Prosecutor Yury Chaika.

The Ukrainian National Service for Security and Defense accuse her of violating article 109 of the Criminal Code, which deals with overthrow of the government.
Poklonskaya became somewhat of an internet sensation due you relative youth, attractive appearance and emotional media conferences. A number of anime-style drawings of the official are currency circulation on the web, with many supporters calling her ‘kawaii prosecutor’ after the Japanese term for cuteness.
The now-wanted in Ukraine officer of the law is somewhat irritated with her web popularity, she told the media, because it undermines the serious nature of her job.
Last week the Ukrainian security service said it was investigating 22 alleged cases under Article 109. Seven of the alleged ‘separatists’, as Kiev calls them, are under arrest. Among those charged are several leaders of protests in eastern Ukraine, which defied the new authorities.

Crimean chief prosecutor Natalia Poklonskaya ‘wanted’ by Ukraine’s security service

Ukrainian national security service has put Crimea’s chief prosecutor Natalia Poklonskaya on its wanted list. She is charged of taking actions aimed at the violent overthrow of constitutional order and takeover of government power.

Poklonskaya took the office as Crimea defied the coup-imposed government in Kiev and sought independence from Ukraine. After the peninsula joined the Russian Federation, she was appointed as Crimea’s acting chief prosecutor by Russia’s General Prosecutor Yury Chaika.

The Ukrainian National Service for Security and Defense accuse her of violating article 109 of the Criminal Code, which deals with overthrow of the government.

Poklonskaya became somewhat of an internet sensation due you relative youth, attractive appearance and emotional media conferences. A number of anime-style drawings of the official are currency circulation on the web, with many supporters calling her ‘kawaii prosecutor’ after the Japanese term for cuteness.

The now-wanted in Ukraine officer of the law is somewhat irritated with her web popularity, she told the media, because it undermines the serious nature of her job.

Last week the Ukrainian security service said it was investigating 22 alleged cases under Article 109. Seven of the alleged ‘separatists’, as Kiev calls them, are under arrest. Among those charged are several leaders of protests in eastern Ukraine, which defied the new authorities.

New Dwarf Planet ‘Biden’ Discovered: 2012 VP113 Is The Most Distant ‘Family Member’ Of The Solar System
Way beyond the orbit of Pluto spins a newly found dwarf planet, 2012 VP113, nicknamed “Biden” by the astronomers. The dwarf planet is believed to be located within the inner Oort cloud, joining the dwarf planet Sedna as a distant member of the solar system.
According to NASA, the discovery of the distant dwarf planet helps define the outer edge of the solar system while also leading to new insights on the mysterious Oort Cloud, considered the “edge” of the solar system. This area could contain up to 2 trillion comets and other objects and is located between 5,000 and 100,000 astronomical units away from the sun, reports NASA. (Each AU is the average distance between the sun and Earth, roughly 93 million miles.) The researchers break up the Oort Cloud into two sections, the much closer inner part, which contains Sedna and the newly discovered dwarf planet, and the outer section, which is believed to be where some comets originate. The Kuiper Belt is located outside of the orbit of Neptune and contains hundreds of thousands of icy objects.

New Dwarf Planet ‘Biden’ Discovered: 2012 VP113 Is The Most Distant ‘Family Member’ Of The Solar System

Way beyond the orbit of Pluto spins a newly found dwarf planet, 2012 VP113, nicknamed “Biden” by the astronomers. The dwarf planet is believed to be located within the inner Oort cloud, joining the dwarf planet Sedna as a distant member of the solar system.

According to NASA, the discovery of the distant dwarf planet helps define the outer edge of the solar system while also leading to new insights on the mysterious Oort Cloud, considered the “edge” of the solar system. This area could contain up to 2 trillion comets and other objects and is located between 5,000 and 100,000 astronomical units away from the sun, reports NASA. (Each AU is the average distance between the sun and Earth, roughly 93 million miles.) The researchers break up the Oort Cloud into two sections, the much closer inner part, which contains Sedna and the newly discovered dwarf planet, and the outer section, which is believed to be where some comets originate. The Kuiper Belt is located outside of the orbit of Neptune and contains hundreds of thousands of icy objects.

DHC会長:「みんな・渡辺代表に8億円」2回の選挙前に
みんなの党の渡辺喜美代表が2010年の参院選と12年の衆院選の前に、大手化粧品販売会社の会長から「計8億円を借り入れていた」と26日発売の 週刊新潮が報じることが分かった。毎日新聞の取材に党幹部は「個人的な借り入れで、金利も払っている」などとしている。同誌は、借り入れた資金について収 支や資産の報告が不十分で、政治活動や選挙活動に使われた場合は政治資金規正法や公職選挙法に抵触する可能性もあると指摘している。
 週刊新潮には、化粧品やサプリメントを販売する「ディーエイチシー(DHC)」(東京都港区)の吉田嘉 明会長(73)が手記を寄せた。それによると、吉田氏は参院選前月の10年6月に3億円、衆院選前月の12年11月には5億円を渡辺代表の個人口座に振り 込んだとしている。その後約2億4700万円が返済され、今も5億円超の借り入れがあるという。一方、12年12月の衆院選で当選した議員を対象とする資 産公開で、渡辺氏は借入金を2億5000万円と記載。手記と食い違う。

 DHCは毎日新聞の取材に「会長と渡辺氏の個人的なことで、会社としてコメントできない」とし、吉田氏も関係者を通じて「今日(25日)はお答えできない」としている。

 一方、渡辺氏の事務所は「記事を見ていない段階では対応できない」としている。関係者によると渡辺氏は26日にもコメントを出す予定という。
 政治資金収支報告書によると、渡辺氏が代表を務める「みんなの党栃木県支部」は、吉田会長から10〜12年に計6000万円の献金を受けた。渡辺氏の資金管理団体なども09〜11年に吉田会長から献金やパーティー券購入で計600万円の提供を受けた。

DHC会長:「みんな・渡辺代表に8億円」2回の選挙前に

みんなの党の渡辺喜美代表が2010年の参院選と12年の衆院選の前に、大手化粧品販売会社の会長から「計8億円を借り入れていた」と26日発売の 週刊新潮が報じることが分かった。毎日新聞の取材に党幹部は「個人的な借り入れで、金利も払っている」などとしている。同誌は、借り入れた資金について収 支や資産の報告が不十分で、政治活動や選挙活動に使われた場合は政治資金規正法や公職選挙法に抵触する可能性もあると指摘している。

 週刊新潮には、化粧品やサプリメントを販売する「ディーエイチシー(DHC)」(東京都港区)の吉田嘉 明会長(73)が手記を寄せた。それによると、吉田氏は参院選前月の10年6月に3億円、衆院選前月の12年11月には5億円を渡辺代表の個人口座に振り 込んだとしている。その後約2億4700万円が返済され、今も5億円超の借り入れがあるという。一方、12年12月の衆院選で当選した議員を対象とする資 産公開で、渡辺氏は借入金を2億5000万円と記載。手記と食い違う。

 DHCは毎日新聞の取材に「会長と渡辺氏の個人的なことで、会社としてコメントできない」とし、吉田氏も関係者を通じて「今日(25日)はお答えできない」としている。

 一方、渡辺氏の事務所は「記事を見ていない段階では対応できない」としている。関係者によると渡辺氏は26日にもコメントを出す予定という。

 政治資金収支報告書によると、渡辺氏が代表を務める「みんなの党栃木県支部」は、吉田会長から10〜12年に計6000万円の献金を受けた。渡辺氏の資金管理団体なども09〜11年に吉田会長から献金やパーティー券購入で計600万円の提供を受けた。

(出典: mainichi.jp)

STAP細胞 実験マウスに新たな疑問

STAP細胞を巡る問題で、小保方晴子研究ユニットリーダーがマウスから作り出したとしていたSTAP細胞 2株の遺伝子を共同研究者が調べたところ、この細胞が、実験に使われていないはずの別の種類のマウスのものだったことが、関係者の証言で分かりました。専 門家は、論文で出来たとされ凍結保存されている8株のSTAP細胞すべてについて詳しく調べるべきだとしています。
これは、神戸市にある理化学研究所発生・再生科学総合研究センターの関係者が、NHKの取材に対し明らかにしたものです。そ れによりますと、遺伝子が調べられたのは、共同研究者の若山照彦山梨大学教授が特殊な処理をして凍結保存していたSTAP細胞2株で、若山教授がどんなマ ウスからでも作製が可能か調べるため、小保方さんに論文の実験で使ったのとは異なる129系統という種類のマウスを手渡し、作製を依頼したものです。小保方さんは、シャーレの中で129系統のマウスの細胞を刺激したところ、状態のよいSTAP細胞の塊が2つ出来たとして若山教授に渡したということです。ところが、一連の問題を受けてこの2株の細胞の遺伝子を調べたところ、細胞は129系統のマウスのものではなく、いずれもこの実験には使っていないはずのB6とF1という2種類のマウスのものだったことが分かりました。今回検出されたB6、F1、それに129の系統のマウスは、いずれも万能細胞の1つ「ES細胞」を作るのによく使われ、研究の現場では、これらのマウスから作ったES細胞が広く実験に使われています。日 本分子生物学会の理事長も務める大隅典子東北大学教授は、「STAP細胞が、実際にはES細胞だったのではないかという疑念を持つ研究者は少なくない。こ うした疑念を晴らすためにも、理化学研究所は、今回の2株だけでなく論文の8株についても遺伝子を詳しく解析し、結果を早急に公表すべきだ」と話していま す。

STAP細胞 実験マウスに新たな疑問

STAP細胞を巡る問題で、小保方晴子研究ユニットリーダーがマウスから作り出したとしていたSTAP細胞 2株の遺伝子を共同研究者が調べたところ、この細胞が、実験に使われていないはずの別の種類のマウスのものだったことが、関係者の証言で分かりました。専 門家は、論文で出来たとされ凍結保存されている8株のSTAP細胞すべてについて詳しく調べるべきだとしています。

これは、神戸市にある理化学研究所発生・再生科学総合研究センターの関係者が、NHKの取材に対し明らかにしたものです。
そ れによりますと、遺伝子が調べられたのは、共同研究者の若山照彦山梨大学教授が特殊な処理をして凍結保存していたSTAP細胞2株で、若山教授がどんなマ ウスからでも作製が可能か調べるため、小保方さんに論文の実験で使ったのとは異なる129系統という種類のマウスを手渡し、作製を依頼したものです。
小保方さんは、シャーレの中で129系統のマウスの細胞を刺激したところ、状態のよいSTAP細胞の塊が2つ出来たとして若山教授に渡したということです。
ところが、一連の問題を受けてこの2株の細胞の遺伝子を調べたところ、細胞は129系統のマウスのものではなく、いずれもこの実験には使っていないはずのB6とF1という2種類のマウスのものだったことが分かりました。
今回検出されたB6、F1、それに129の系統のマウスは、いずれも万能細胞の1つ「ES細胞」を作るのによく使われ、研究の現場では、これらのマウスから作ったES細胞が広く実験に使われています。
日 本分子生物学会の理事長も務める大隅典子東北大学教授は、「STAP細胞が、実際にはES細胞だったのではないかという疑念を持つ研究者は少なくない。こ うした疑念を晴らすためにも、理化学研究所は、今回の2株だけでなく論文の8株についても遺伝子を詳しく解析し、結果を早急に公表すべきだ」と話していま す。

(出典: www3.nhk.or.jp)

Prosecutors poised to charge ex-Tokyo Gov. Inose over funds


Prosecutors are poised to charge former Tokyo Gov. Naoki Inose at a summary court with failure to report election funds over ¥50 million he received from a major hospital chain, sources said Tuesday.
Inose, 67, has repeatedly said the money given by Tokushukai was a personal loan, but the prosecutors have determined it was campaign funds for the 2012 gubernatorial election and that his failure to report it violates the Public Offices Election Law, the sources said.
Inose was elected Tokyo governor in December 2012 but stepped down about a year later over the money scandal.

Prosecutors poised to charge ex-Tokyo Gov. Inose over funds

Prosecutors are poised to charge former Tokyo Gov. Naoki Inose at a summary court with failure to report election funds over ¥50 million he received from a major hospital chain, sources said Tuesday.

Inose, 67, has repeatedly said the money given by Tokushukai was a personal loan, but the prosecutors have determined it was campaign funds for the 2012 gubernatorial election and that his failure to report it violates the Public Offices Election Law, the sources said.

Inose was elected Tokyo governor in December 2012 but stepped down about a year later over the money scandal.

(出典: japantimes.co.jp)

Search for missing Malaysian airliner turns up no new debris sightings

A growing number of airplanes scoured the southern Indian Ocean on Sunday as the 16-day search for Malaysia Airlines Flight 370 continued, but the end result was frustratingly the same — nothing.

Buoyed by a third set of satellite data that indicated possible debris from the plane in the water, the international team led by Australia fought bad weather early in the day as it looked for signs of the missing Boeing 777 and the 239 people who were aboard.

Eight aircraft and one ship conducted Sunday’s search and there were no sightings of significance, the Australian Maritime Safety Authority said in a written statement.

Four more jets — two from China and two from Japan — are set to join the reconnaissance team on Monday, the organization said.

Earlier, French authorities passed on satellite data showing “potential objects in the vicinity of the southern corridor” of the search area for the plane, Malaysia’s acting transportation minister said.

"Malaysia immediately relayed these images to the Australian rescue coordination center," Hishammuddin Hussein said.

Satellite images previously issued by Australian and Chinese authorities have also pointed to possible large floating objects, stoking hopes searchers may find debris from the missing plane.

Sunday’s search was a visual search, AMSA rescue spokesman Mike Barton told reporters. Eyes took precedence over radar. Four of the planes were civil aircraft, each with five volunteers from Australia who scanned the water.

Pallet found

(出典: CNN)

Protocol for generating STAP cells from mature somatic cells
We have found this to be an effective protocol for generating STAP cells in our lab, regardless of the cell type being studied. The protocol below is a combination of the two most effective approaches described in our Jan 31, 2014 article published in Nature (Obokata et al., Stimulus Triggered Fate Conversion of Somatic Cells into Pluripotency. Nature 505. 641-647, 2014). It is very important that each step be performed precisely as described. The protocol is extremely simple, but will vary slightly if you are starting with tissue rather than a cell suspension. It also will vary depending upon the cell type or tissue with which you are starting. It is important to not skip any steps. It is especially important to triturate the cell suspension for a minimum of 30 minutes, until the suspension can be easily triturated up and down the reduced bore pipettes of the smallest orifices. We first describe the protocol when starting with a suspension of cells, and then describe additional steps necessary when starting with a soft tissue.
——

Continue to triturate the suspension until it passes easily up and down the fire polished pipette of the smaller bore. This is a very important step. Do not skip this step, or take a shortcut. Again, remember to precoat a each pipette with media.

Protocol for generating STAP cells from mature somatic cells

We have found this to be an effective protocol for generating STAP cells in our lab, regardless of the cell type being studied. The protocol below is a combination of the two most effective approaches described in our Jan 31, 2014 article published in Nature (Obokata et al., Stimulus Triggered Fate Conversion of Somatic Cells into Pluripotency. Nature 505. 641-647, 2014). It is very important that each step be performed precisely as described. The protocol is extremely simple, but will vary slightly if you are starting with tissue rather than a cell suspension. It also will vary depending upon the cell type or tissue with which you are starting. It is important to not skip any steps. It is especially important to triturate the cell suspension for a minimum of 30 minutes, until the suspension can be easily triturated up and down the reduced bore pipettes of the smallest orifices. We first describe the protocol when starting with a suspension of cells, and then describe additional steps necessary when starting with a soft tissue.

——

Continue to triturate the suspension until it passes easily up and down the fire polished pipette of the smaller bore. This is a very important step. Do not skip this step, or take a shortcut. Again, remember to precoat a each pipette with media.

(出典: research.bwhanesthesia.org)

Australia Says It May Have Spotted Two Pieces of MH370 Debris

Here are the two images of the debris, released and annotated by AMSA

Australia Says It May Have Spotted Two Pieces of MH370 Debris

Here are the two images of the debris, released and annotated by AMSA

(出典: thewire.com)